DAXX Antibody - middle region
Produktgrößen
100ul
£359,00
OASG02090-100UL
Über dieses Produkt
- SKU:
- OASG02090
- Zusätzliche Namen:
- DAP6; EAP1; BING2; SMIM40
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins; such as apoptosis antigen Fas; centromere protein C; and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus; the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm; the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications; including sumoylation; phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
- Gendetails:
- death-domain associated protein
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human Daxx. Location: 330-410aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 100 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php