EIF4G2 Antibody - N-terminal region
Produktgrößen
100ul
£359,00
OASG02078-100UL
Über dieses Produkt
- SKU:
- OASG02078
- Zusätzliche Namen:
- P97; AAG1; DAP5; NAT1
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F); which is a cap binding protein complex that consists of three subunits: eIF4A; eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G; in addition; contains a binding site for eIF4E at the N-terminus. Unlike eIF4G; which supports cap-dependent and independent translation; this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
- Gendetails:
- eukaryotic translation initiation factor 4 gamma; 2
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the N-terminal region of human DAP-5. Location: 10-90aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 90 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php