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Antikörper

CTTN Antibody

Produktgrößen
100ul
£359,00
OASG01767-100UL
Über dieses Produkt
SKU:
OASG01767
Zusätzliche Namen:
EMS1
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis; the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Gendetails:
cortactin
Host:
Rabbit
Immunogen:
Synthesized peptide derived from the Internal region of human Cortactin around the acetylation site of K235.
Isotyp:
IgG
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20C. Avoid repeated freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody