CHEK1 Antibody
Produktgrößen
100ul
£359,00
OASG01543-100UL
Über dieses Produkt
- SKU:
- OASG01543
- Zusätzliche Namen:
- CHK1
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR; two cell cycle proteins involved in DNA damage responses; that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
- Gendetails:
- checkpoint kinase 1
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Chk1 around the phosphorylation site of S280. Location: 220-300aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 54/60 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php