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Antikörper

CEACAM1 Antibody - N-terminal region

Produktgrößen
100ul
£359,00
OASG01467-100UL
Über dieses Produkt
SKU:
OASG01467
Zusätzliche Namen:
BGP; BGP1; BGPI
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family; which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family; the CEA cell adhesion molecules and the pregnancy-specific glycoproteins; are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently; it was found to be a cell-cell adhesion molecule detected on leukocytes; epithelia; and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein; including roles in the differentiation and arrangement of tissue three-dimensional structure; angiogenesis; apoptosis; tumor suppression; metastasis; and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported; but the full-length nature of all variants has not been defined.
Gendetails:
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
Host:
Rabbit
Immunogen:
Synthesized peptide derived between 31-80 amino acids from the N-terminal region of human CEACAM1/5.
Isotyp:
IgG
Molekulargewicht:
58 kDa
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20C. Avoid repeated freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody