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Antikörper

GP5 Antibody - middle region

Produktgrößen
100ul
£359,00
OASG01310-100UL
Über dieses Produkt
SKU:
OASG01310
Zusätzliche Namen:
GPV; CD42d
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation; a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains; an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720); that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA; GP1BB; and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200); a bleeding disorder (review by Lopez et al.; 1998 [PubMed 9616133]).[supplied by OMIM; Nov 2010]
Gendetails:
glycoprotein V (platelet)
Host:
Rabbit
Immunogen:
Synthesized peptide derived from the Internal region of human CD42d.
Isotyp:
IgG
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20C. Avoid repeated freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody