FCGR3A Antibody
Produktgrößen
100ul
£392,00
OASG01193-100UL
Über dieses Produkt
- SKU:
- OASG01193
- Zusätzliche Namen:
- CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a receptor for the Fc portion of immunoglobulin G; and it is involved in the removal of antigen-antibody complexes from the circulation; as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide; whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections; susceptibility to systemic lupus erythematosus; and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Gendetails:
- Fc fragment of IgG; low affinity IIIa; receptor (CD16a)
- Host:
- Mouse
- Immunogen:
- Synthetic Peptide
- Aufreinigung:
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php