CREBBP Antibody
Produktgrößen
100ul
£359,00
OASG01132-100UL
Über dieses Produkt
- SKU:
- OASG01132
- Zusätzliche Namen:
- CBP; RSTS; KAT3A; MKHK1; RSTS1
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Acetylates histones; giving a specific tag for transcriptional activation. Also acetylates non-histone proteins; like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA; acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) .
- Gendetails:
- CREB binding protein
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived between 1480-1550 aa from human CBP around the non-acetylation site of K1535.
- Isotyp:
- IgG
- Molekulargewicht:
- 265 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20°C; and avoid repeat freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php