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Antikörper

CASR Antibody

Produktgrößen
100ul
£359,00
OASG01065-100UL
Über dieses Produkt
SKU:
OASG01065
Zusätzliche Namen:
CAR; FHH; FIH; HHC; EIG8; HHC1; NSHPT; PCAR1; hCasR; GPRC2A; HYPOC1
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland; and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling; thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia; familial; isolated hypoparathyroidism; and neonatal severe primary hyperparathyroidism.
Gendetails:
calcium-sensing receptor
Host:
Rabbit
Immunogen:
Synthesized peptide derived from human CaSR around the phosphorylation site of T888. Location: 830-910aa.
Isotyp:
IgG
Molekulargewicht:
140 kDa
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20C. Avoid repeated freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody