CASP9 Antibody
Produktgrößen
100ul
£359,00
OASG01056-100UL
Über dieses Produkt
- SKU:
- OASG01056
- Zusätzliche Namen:
- MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits; large and small; that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome; a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
- Gendetails:
- caspase 9; apoptosis-related cysteine peptidase
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Caspase-9 around the phosphorylation site of S144. Location: 80-160aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 35 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php