CASP3 Antibody
Produktgrößen
100ul
£359,00
OASG01022-100UL
Über dieses Produkt
- SKU:
- OASG01022
- Zusätzliche Namen:
- CPP32; SCA-1; CPP32B
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits; large and small; that dimerize to form the active enzyme. This protein cleaves and activates caspases 6; 7 and 9; and the protein itself is processed by caspases 8; 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein; which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
- Gendetails:
- caspase 3; apoptosis-related cysteine peptidase
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Caspase-3 around the phosphorylation site of S150. Location: 90-170aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 34 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php