CASP1 Antibody
Produktgrößen
100ul
£359,00
OASG01013-100UL
Über dieses Produkt
- SKU:
- OASG01013
- Zusätzliche Namen:
- ICE; P45; IL1BC
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits; large and small; that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1; a cytokine involved in the processes such as inflammation; septic shock; and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
- Gendetails:
- caspase 1; apoptosis-related cysteine peptidase
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human Caspase-1 p20. Location: 70-150aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 18 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php