CARD14 Antibody - middle region
Produktgrößen
100ul
£359,00
OASG00986-100UL
Über dieses Produkt
- SKU:
- OASG00986
- Zusätzliche Namen:
- PRP; PSS1; BIMP2; CARMA2; PSORS2
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1; and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14-induced activation of NF-kappa-B and p38/JNK MAP kinases . May play a role in signaling mediated by TRAF2; TRAF3 and TRAF6 and protects cells against apoptosis. ; Isoform 3: Not able to activate the inflammatory transcription factor NF-kappa-B and may fuction as a dominant negative regulator.
- Gendetails:
- caspase recruitment domain family; member 14
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human CARD 14. Location: 260-340aa (Internal)
- Isotyp:
- IgG
- Molekulargewicht:
- 110 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php