ATRX Antibody - N-terminal region
Produktgrößen
100ul
£359,00
OASG00656-100UL
Über dieses Produkt
- SKU:
- OASG00656
- Zusätzliche Namen:
- JMS; XH2; XNP; MRX52; RAD54; RAD54L; ZNF-HX
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene contains an ATPase/helicase domain; and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation; which regulates its nuclear matrix and chromatin association; and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation; which may provide a link between chromatin remodeling; DNA methylation; and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
- Gendetails:
- alpha thalassemia/mental retardation syndrome X-linked
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived between 80-160 aa from the N-terminal region of human ATRX.
- Isotyp:
- IgG
- Molekulargewicht:
- 283 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C; and avoid repeat freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php