APLP2 Antibody
Produktgrößen
100ul
£359,00
OASG00456-100UL
Über dieses Produkt
- SKU:
- OASG00456
- Zusätzliche Namen:
- APPH; APPL2; CDEBP; APLP-2
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes amyloid precursor- like protein 2 (APLP2); which is a member of the APP (amyloid precursor protein) family including APP; APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-; copper- and zinc- binding domains at the N-terminus; BPTI/Kunitz inhibitor and E2 domains in the middle region; and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission; spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- Gendetails:
- amyloid beta (A4) precursor-like protein 2
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human APLP2 around the phosphorylation site of Y755. Location: 690-770aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 87 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php