APAF1 Antibody - middle region
Produktgrößen
100ul
£359,00
OASG00437-100UL
Über dieses Produkt
- SKU:
- OASG00437
- Zusätzliche Namen:
- CED4; APAF-1
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain; a caspase recruitment domain (CARD); and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP; this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein; releasing its mature; activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
- Gendetails:
- apoptotic peptidase activating factor 1
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human Apaf-1.
- Isotyp:
- IgG
- Molekulargewicht:
- 135 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php