AIRE Antibody
Produktgrößen
100ul
£359,00
OASG00251-100UL
Über dieses Produkt
- SKU:
- OASG00251
- Zusätzliche Namen:
- APS1; APSI; PGA1; AIRE1; APECED
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
- Gendetails:
- autoimmune regulator
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human AIRE-1 around the phosphorylation site of S156. Location: 100-180aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 50 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php