ALOX5 Antibody
Produktgrößen
100ul
£359,00
OASG00074-100UL
Über dieses Produkt
- SKU:
- OASG00074
- Zusätzliche Namen:
- 5-LO; 5LPG; LOG5; 5-LOX
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein; which is expressed specifically in bone marrow-derived cells; catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8;11;14-cis-eicosatetraenoic acid; and further to the allylic epoxide 5(S)-trans-7;9-trans-11;14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Gendetails:
- arachidonate 5-lipoxygenase
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human 5-LO around the phosphorylation site of S523. Location: 470-550aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 77 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php