EIF4EBP1 Antibody
Produktgrößen
100ul
£359,00
OASG00060-100UL
Über dieses Produkt
- SKU:
- OASG00060
- Zusätzliche Namen:
- BP-1; 4EBP1; 4E-BP1; PHAS-I
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E); which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling; resulting in its dissociation from eIF4E and activation of mRNA translation.
- Gendetails:
- eukaryotic translation initiation factor 4E binding protein 1
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human 4E-BP1 around the phosphorylation site of T46. Location: 30-110aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 12/35 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php