CHM Antibody - N-terminal region
Produktgrößen
200 ul
£463,00
OASF00038-200UL
Über dieses Produkt
- SKU:
- OASF00038
- Zusätzliche Namen:
- TCD; GGTA; REP-1; DXS540; HSD-32
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 3 mg/ml
- Weitere Details:
- This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme; this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid; retinal pigment epithelium and retina. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Gendetails:
- choroideremia (Rab escort protein 1)
- Host:
- Goat
- Immunogen:
- Purified recombinant peptide derived from within residues 1-80 aa at the N-terminus of rat Rep1 produced in E. coli.
- Isotyp:
- IgG
- Aufreinigung:
- Epitope-affinity purified from goat antiserum.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For continuous use; store at 2-8 C for one-two days. For extended storage; store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php