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Antikörper

CHAT Antibody

Produktgrößen
100 ul
£587,00
OAPC00231-100UL
Über dieses Produkt
SKU:
OAPC00231
Zusätzliche Namen:
CMS6; CMS1A; CMS1A2; CHOACTASE
Klonalität:
Polyclonal
Weitere Details:
Choline acetyltransferase is a neuronal enzyme which catalyzes the reaction between Acetyl CoA and choline resulting in the formation of acetylcholine. It is therefore found primarily in cholinergic neurons making it a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia; Alzheimer disease (AD) and Down syndrome (Holt et al. 1999). Decreased choline acetyltransferase activity in particular has been shown in Schizophrenic subjects (Karson et al 1993). It has furthermore been demonstrated that in patients with AD; there are significantly lower levels of cortical ChAT that correlate with severity of the disease as measured by loss of neuropsychological function (Baskin et al. 1999).
Gendetails:
choline O-acetyltransferase
Host:
Goat
Immunogen:
Native choline acetyltransferase purifed from human placenta
Molekulargewicht:
70 kDa
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For long term storage -20C is recommended. Stable at -20C for at least 1 year. Avoid freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody