GABAB R2 Antibody
Produktgrößen
100 ul
£587,00
OAPC00163-100UL
Über dieses Produkt
- SKU:
- OAPC00163
- Zusätzliche Namen:
- Gpr51
- Klonalität:
- Polyclonal
- Weitere Details:
- Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. It has recently been demonstrated that AMPK binds directly to GABAB receptors and phosphorylates S783 in the cytoplasmic tail of the R2 subunit and that S783 plays a critical role in enhancing neuronal survival after ischemia as phosphorylation of S783 is evident in many brain regions and is increased dramatically after ischemic injury to the brain (Kuramoto et al.; 2007).
- Host:
- Rabbit
- Immunogen:
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser783 of GABAB R2.
- Molekulargewicht:
- ~102kDa
- Proteindetails:
- Gamma-aminobutyric acid type B receptor subunit 2
- Aufreinigung:
- Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephospho-peptide affinity columns.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C; stable for at least one year.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php