Connexin43 Antibody
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100 ul
£587,00
OAPC00147-100UL
Über dieses Produkt
- SKU:
- OAPC00147
- Zusätzliche Namen:
- Cx43; Cxnk1
- Klonalität:
- Polyclonal
- Weitere Details:
- Gap junctional intercellular communication is thought to play a key role in development and may also be involved in epilepsy (Aronica et al.; 2001). Connexin43 forms gap-junctional channels and regulates the permeability of these gap junctions to small organic molecules. Permeability of connexin43 is known to be regulated by phosphorylation at Ser368 by protein kinase C (Yogo et al.; 2002; Bao et al.; 2004a). Phosphorylation of Ser368 by PKC induces a conformational change of connexin43 that results in a decrease in gap junction permeability (Bao et al.; 2004b).
- Host:
- Rabbit
- Immunogen:
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser368 of rat connexin43.
- Molekulargewicht:
- ~43kDa
- Proteindetails:
- Gap junction alpha-1 protein
- Aufreinigung:
- Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C; stable for at least one year.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php