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Antikörper

Anti-GAP-43

Produktgrößen
100 ul
£522,00
OAPC00136-100UL
Über dieses Produkt
SKU:
OAPC00136
Zusätzliche Namen:
Basp2
Klonalität:
Polyclonal
Konzentration:
15 mg/ml
Weitere Details:
GAP-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration (Benowitz and Routtenberg; 1997). There is also evidence from knockout animals that GAP-43 serves to amplify pathfinding signals from the growth cone (Strittmatter et al.; 1995). GAP-43 is thought to mediate at least some of these effects via interaction with actin. Importantly; phosphorylation at Ser41 by protein kinase C modulates the interaction of GAP-43 with actin (He et al.; 1997) and may also affect neurotransmitter release during forms of plasticity like LTP (Hulo et al.; 2002).
Immunogen:
Synthetic peptide corresponding to amino acid residues from the C-terminal region of the rat GAP43 sequence.
Molekulargewicht:
~43kDa
Proteindetails:
Neuromodulin
Aufreinigung:
Total IgY fraction.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For long term storage -20C is recommended. Stable at -20C for at least 1 year.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody