GLRA1 Antibody
Produktgrößen
200 ug
£587,00
OAPC00117-200UG
Über dieses Produkt
- SKU:
- OAPC00117
- Zusätzliche Namen:
- GLYRA1
- Klonalität:
- Polyclonal
- Weitere Details:
- Glycine is an important inhibitory transmitter in the brainstem and spinal cord. Glycine receptors are members of the ligand-gated ion channel family (LGICs) that mediate rapid chemical neurotransmission (Schofield et al.; 2003). The binding of glycine to its receptor produces a large increase in chloride conductance; which causes membrane hyperpolarization. Glycine receptors are anchored at inhibitory chemical synapses by a cytoplasmic protein; gephyrin (Fischer et al.; 2000). The glycine receptor has been used to great advantage in the identification of the binding sites for alcohol on the LGIC family of proteins (Beckstead et al.; 2001; Mihic et al.; 1997). These receptors have also been extremely useful in studies of synaptic clustering of receptors (Craig and Lichtman; 2001). The glycine receptor may also act in concert with an NMDAR subunit to form an excitatory receptor (Chatterton et al.; 2002).
- Host:
- Rabbit
- Immunogen:
- Peptide from the N-terminus region of the alpha 1-subunit of rat glycine receptor.
- Molekulargewicht:
- ~48kDa
- Proteindetails:
- Glycine receptor subunit alpha-1; Glycine receptor subunit alpha-2
- Aufreinigung:
- Prepared from rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Packaging: 200 ug antibody vial; lyophilized from 5 mM ammonium bicarbonate.Adequate amount of material to conduct 10-mini Western Blots.
Reconstitution: The antibody should be reconstituted in 100 ul phosphate buffered saline (PBS: 137 mM NaCl; 7.5 mM Na2HPO4; 2.7 mM KCl; 1.5 mM KH2HPO4; pH 7.4) before use.
Storage: After reconstitution the antibody should be aliquoted and stored at -20C. - Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php