Anti-Collagen I alpha 1 Telopeptide Sequence
Produktgrößen
100 ul
£587,00
OAPC00095-100UL
Über dieses Produkt
- SKU:
- OAPC00095
- Zusätzliche Namen:
- OI1; OI2; OI3; OI4; EDSC; CAFYD; EDSARTH1
- Klonalität:
- Polyclonal
- Weitere Details:
- Collagen is an extracellular matrix protein that serves as a scaffold defining the shape and mechanical properties of many tissues and organs including skin; tendon; artery walls; fibrocartilage; bone and teeth. Type 1 collagen is the most abundant protein in mammals. Collagens are synthesized with N-terminal and C-terminal propeptides that are cleaved during maturation and secretion. After cleavage of the propeptides; the most N-terminal and C-terminal remaining sequences are known as telopeptides. Mutations in the collagen 1; alpha 1 gene (COL1A1) are known to cause osteogenesis imperfecta (aka brittle bone disease) (Byers 1989). Furthermore; mutations found in the fist 90 residues of the helical region of alpha 1 collagen have been implicated in the prevention or delayed removal of the procollagen N-propeptide leading to a combined osteogenesis imperfecta and Ehlers-Danlos syndrome (EDS) phenotype (Cabral et al.; 2005).
- Host:
- Rabbit
- Immunogen:
- Peptide from the human collagen I alpha 1 telopeptide sequence.
- Molekulargewicht:
- ~140kDa
- Proteindetails:
- Collagen alpha-1(I) chain
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C; stable for at least one year.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: Collagen
- Datenblatt des Herstellers:html_datasheet.php