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Antikörper

Anti-Beta III Tubulin

Produktgrößen
100 ul
£587,00
OAPC00075-100UL
Über dieses Produkt
SKU:
OAPC00075
translate.label.attr.clone:
AA10
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
Tubulin is the major constituent of microtubules; existing as a heterodimer of the alpha and beta subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific; posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins (Lee et al.; 1990). Additionally; beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer; large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al.; 2003)
Host:
Mouse
Immunogen:
Synthetic peptide corresponding to beta III tubulin.
Isotyp:
IgG
Molekulargewicht:
~55kDa
Proteindetails:
Tubulin beta-3 chain
Aufreinigung:
Protein G purified culture supernatant.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For long-term storage; -80C is recommended; but shorter-term storage at -20C is also acceptable as aliquots may be taken without freezing/thawing due to the presence of 50% glycerol. Stock solutions are stable for a minimum of 1 year at -20C.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody