DAF Antibody - C-terminal
Produktgrößen
0.1 mg
£652,00
OAPB01940-0.1MG
Über dieses Produkt
- SKU:
- OAPB01940
- Zusätzliche Namen:
- CD55 antigen;CD55 molecule; decay accelerating factor for complement (Cromer blood group);CHAPLE;complement decay-accelerating factor;CR;CROM;Cromer blood group antigen;DAF;Rh blood group D antigen;TC.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb; the amplification convertases of the complement cascade (PubMed:7525274). Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases; which prevents complement damage (PubMed:28657829).
- Gendetails:
- CD55 molecule (Cromer blood group)
- Host:
- Rabbit
- Immunogen:
- DAF antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DAF. The immunogen is located within amino acids 360 - 410 of DAF.
- Isotyp:
- IgG
- Molekulargewicht:
- Predicted: 48 kDa Observed: 49 kDa
- Proteindetails:
- Complement decay-accelerating factor|complement decay-accelerating factor isoform 2 precursor [Homo sapiens]
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php