CASR Antibody - N-terminal
Produktgrößen
0.1 mg
£652,00
OAPB01896-0.1MG
Über dieses Produkt
- SKU:
- OAPB01896
- Zusätzliche Namen:
- CAR;EIG8;extracellular calcium-sensing receptor;FHH;FIH;GPRC2A;hCasR;HHC;HHC1;HYPOC1;NSHPT;parathyroid Ca(2+)-sensing receptor 1;parathyroid cell calcium-sensing receptor 1;PCAR1.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis (PubMed:7759551; PubMed:8702647; PubMed:8636323; PubMed:8878438; PubMed:17555508; PubMed:19789209; PubMed:21566075; PubMed:22114145; PubMed:23966241; PubMed:25292184; PubMed:25104082; PubMed:26386835; PubMed:25766501; PubMed:22789683). Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (By similarity). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:7759551). The G-protein-coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids; such as Trp or Phe; act concertedly with divalent cations; such as calcium or magnesium; to achieve full receptor activation (PubMed:27434672; PubMed:27386547).
- Gendetails:
- calcium sensing receptor
- Host:
- Rabbit
- Immunogen:
- CASR antibody was raised against a 15 amino acid peptide near the amino terminus of human CASR. The immunogen is located within the first 50 amino acids of CASR.
- Isotyp:
- IgG
- Molekulargewicht:
- Predicted: 101; 120 kDa Observed: 115; 125 kDa
- Proteindetails:
- Extracellular calcium-sensing receptor|extracellular calcium-sensing receptor isoform 1 precursor [Homo sapiens]
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php