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Antikörper

GRK6 Antibody - C-terminal

Produktgrößen
0.1 mg
£652,00
OAPB01846-0.1MG
Über dieses Produkt
SKU:
OAPB01846
Zusätzliche Namen:
G protein-coupled receptor kinase 6;G protein-coupled receptor kinase GRK6;GPRK6.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Konzentration:
1 mg/ml
Weitere Details:
Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization; internalization; and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
Gendetails:
G protein-coupled receptor kinase 6
Host:
Rabbit
Immunogen:
GRK6 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human GRK6. The immunogen is located within the last 50 amino acids of GRK6.
Isotyp:
IgG
Molekulargewicht:
Predicted: 63 kDa Observed: 63 kDa
Proteindetails:
G protein-coupled receptor kinase 6|G protein-coupled receptor kinase 6 isoform A [Homo sapiens]
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody