AIMP1 Antibody - C-terminal
Produktgrößen
0.1 mg
£652,00
OAPB01814-0.1MG
Über dieses Produkt
- SKU:
- OAPB01814
- Zusätzliche Namen:
- aminoacyl tRNA synthase complex-interacting multifunctional protein 1;ARS-interacting multifunctional protein 1;EMAP2;EMAPII;endothelial monocyte-activating polypeptide 2;endothelial-monocyte activating polypeptide II;HLD3;multisynthase complex auxiliary component p43;multisynthetase complex auxiliary component p43;p43;SCYE1;small inducible cytokine subfamily E; member 1 (endothelial monocyte-activating).
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase (PubMed:10358004). Binds tRNA. Possesses inflammatory cytokine activity (PubMed:11306575). Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation (By similarity). Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels (By similarity). Promotes dermal fibroblast proliferation and wound repair (PubMed:16472771). Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum (By similarity). Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations (PubMed:12237313). Induces maturation of dendritic cells and monocyte cell adhesion (PubMed:11818442). Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7 (PubMed:19362550).
- Gendetails:
- aminoacyl tRNA synthetase complex interacting multifunctional protein 1
- Host:
- Rabbit
- Immunogen:
- AIMP1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AIMP1. The immunogen is located within amino acids 240 - 290 of AIMP1.
- Isotyp:
- IgG
- Molekulargewicht:
- Predicted: 46 kDa Observed: 36 kDa
- Proteindetails:
- Aminoacyl tRNA synthase complex-interacting multifunctional protein 1|aminoacyl tRNA synthase complex-interacting multifunctional protein 1 isoform b precursor [Homo sapiens]
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php