ERAP1 Antibody - C-terminal
Produktgrößen
0.1 mg
£652,00
OAPB01794-0.1MG
Über dieses Produkt
- SKU:
- OAPB01794
- Zusätzliche Namen:
- adipocyte-derived leucine aminopeptidase;ALAP;A-LAP;aminopeptidase PILS;aminopeptidase regulator of TNFR1 shedding;APPILS;ARTS1;ARTS-1;CTD-2260A17.2;endoplasmic reticulum aminopeptidase 1;endoplasmic reticulum aminopeptidase associated with antigen processing;ERAAP;ERAAP1;PILSAP;PILS-AP;puromycin-insensitive leucyl-specific aminopeptidase;type 1 tumor necrosis factor receptor shedding aminopeptidase regulator.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Aminopeptidase that plays a central role in peptide trimming; a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus; while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.
- Gendetails:
- endoplasmic reticulum aminopeptidase 1
- Host:
- Rabbit
- Immunogen:
- ERAP1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ERAP. The immunogen is located within amino acids 730 - 780 of ERAP1 .
- Isotyp:
- IgG
- Molekulargewicht:
- Predicted: 104 kDa Observed: 105kDa
- Proteindetails:
- Endoplasmic reticulum aminopeptidase 1|endoplasmic reticulum aminopeptidase 1 isoform a precursor [Homo sapiens]
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php