DHX36 Antibody - C-terminal
Produktgrößen
0.1 mg
£652,00
OAPB01692-0.1MG
Über dieses Produkt
- SKU:
- OAPB01692
- Zusätzliche Namen:
- ATP-dependent DNA/RNA helicase DHX36;ATP-dependent RNA helicase DHX36;DDX36;DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 36;DEAD/H box polypeptide 36;DEAH (Asp-Glu-Ala-His) box polypeptide 36;DEAH box protein 36;G4 resolvase-1;G4R1;G4-resolvase 1;MLEL1;MLE-like protein 1;probable ATP-dependent RNA helicase DHX36;RHAU;RNA helicase associated with AU-rich element ARE;RNA helicase associated with AU-rich element protein.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regulates their expression. Binds to telomerase RNA template component (TERC) 5'-end (nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5'-end to promote P1 helix formation; the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification.
- Gendetails:
- DEAH-box helicase 36
- Host:
- Rabbit
- Immunogen:
- Rabbit polyclonal DHX36 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DHX36. The immunogen is located within the last 50 amino acids of DHX36.
- Isotyp:
- IgG
- Molekulargewicht:
- Predicted: 111 kDa
- Proteindetails:
- ATP-dependent RNA helicase DHX36|ATP-dependent RNA helicase DHX36 isoform 1 [Homo sapiens]
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php