FAM193B Antibody - N-terminal
Produktgrößen
0.1 mg
£652,00
OAPB01612-0.1MG
Über dieses Produkt
- SKU:
- OAPB01612
- Zusätzliche Namen:
- IRIZIO;protein FAM193B.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- FAM193B Antibody: FAM193B; also known as IRIZIO; was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS); a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that; in addition to the PAX3-FOXO1 gene fusion; disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway; FAM193B expression enabled the tumorigenic transformation; suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.
- Gendetails:
- family with sequence similarity 193 member B
- Host:
- Rabbit
- Immunogen:
- FAM193B antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human FAM193B. The immunogen is located within amino acids 120 - 170 of FAM193B.
- Isotyp:
- IgG
- Molekulargewicht:
- 99 kDa
- Proteindetails:
- Protein FAM193B
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php