EPAC1 Antibody - N-terminal
Produktgrößen
0.1 mg
£652,00
OAPB01518-0.1MG
Über dieses Produkt
- SKU:
- OAPB01518
- Zusätzliche Namen:
- 9330170P05Rik;bcm910;CAMP-GEFI;cAMP-regulated guanine nucleotide exchange factor I;EPAC;EPAC 1;EPAC1;exchange factor directly activated by cAMP 1;exchange protein directly activated by cAMP 1;HSU79275;Rap guanine nucleotide exchange factor (GEF) 3;rap guanine nucleotide exchange factor 3;Rap1 guanine-nucleotide-exchange factor directly activated by cAMP.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions; such as stress fibers and junctional actin.
- Gendetails:
- Rap guanine nucleotide exchange factor 3
- Host:
- Rabbit
- Immunogen:
- EPAC1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human EPAC1. The immunogen is located within amino acids 60 - 110 of EPAC1.
- Isotyp:
- IgG
- Proteindetails:
- Rap guanine nucleotide exchange factor 3|rap guanine nucleotide exchange factor 3 isoform a [Homo sapiens]
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php