DISP2 Antibody - N-terminal
Produktgrößen
0.1 mg
£652,00
OAPB01434-0.1MG
Über dieses Produkt
- SKU:
- OAPB01434
- Zusätzliche Namen:
- C15orf36;dispatched B;DISPB;HsT16908;LINC00594;long intergenic non-protein coding RNA 594;protein dispatched homolog 2.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- DISP2 Antibody: DISP2 is the second of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis; tissue regeneration; and carcinogenesis and the DISP proteins have been implicated in these pathways. Recently; it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants.
- Gendetails:
- dispatched RND transporter family member 2
- Host:
- Rabbit
- Immunogen:
- DISP2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human DISP2. The immunogen is located within amino acids 110 - 160 of DISP2.
- Isotyp:
- IgG
- Proteindetails:
- Protein dispatched homolog 2
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php