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Antikörper

ENC-2 Antibody

Produktgrößen
0.1 mg
£652,00
OAPB01083-0.1MG
Über dieses Produkt
SKU:
OAPB01083
Zusätzliche Namen:
BTB/POZ KELCH domain protein;ectodermal-neural cortex 2;ectoderm-neural cortex protein 2;ENC2;ENC-2;kelch-like 25;kelch-like protein 25.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Konzentration:
1 mg/ml
Weitere Details:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low. The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E.
Gendetails:
kelch like family member 25
Immunogen:
ENC-2 antibody was raised against a 14 amino acid synthetic peptide near the center of human ENC-2. The immunogen is located within amino acids 230 - 280 of ENC-2.
Proteindetails:
ENC2 [Homo sapiens]|Kelch-like protein 25
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
ENC-2 antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody