CDC42 Antibody
Produktgrößen
0.1 mg
£652,00
OAPB00856-0.1MG
Über dieses Produkt
- SKU:
- OAPB00856
- Zusätzliche Namen:
- CDC42Hs;cell division control protein 42 homolog;dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein; 25kD));dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein; 25kD));G25K;G25K GTP-binding protein;growth-regulating protein;GTP binding protein; 25kDa;small GTP binding protein CDC42;TKS.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin; actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration. Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons. Facilitates filopodia formation upon DOCK11-activation (By similarity). Also plays a role in phagocytosis through organization of the F-actin cytoskeleton associated with forming phagocytic cups.
- Gendetails:
- cell division cycle 42
- Immunogen:
- CDC42 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CDC42. The immunogen is located within amino acids 40 - 90 of CDC42.
- Proteindetails:
- Cell division control protein 42 homolog|cell division control protein 42 homolog isoform 1 precursor [Homo sapiens]
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- CDC42 antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php