GAPDH Antibody
Produktgrößen
0.1 mg
£652,00
OAPB00826-0.1MG
Über dieses Produkt
- SKU:
- OAPB00826
- Zusätzliche Namen:
- aging-associated gene 9 protein;epididymis secretory sperm binding protein Li 162eP;G3PD;GAPD;glyceraldehyde-3-phosphate dehydrogenase;HEL-S-162eP;OCAS; p38 component;Oct1 coactivator in S phase; 38 Kd component;peptidyl-cysteine S-nitrosylase GAPDH.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities; thereby playing a role in glycolysis and nuclear functions; respectively. Participates in nuclear events including transcription; RNA transport; DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1; HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.
- Gendetails:
- glyceraldehyde-3-phosphate dehydrogenase
- Immunogen:
- GAPDH antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human GAPDH. The immunogen is located within amino acids 60 - 110 of GAPDH.
- Proteindetails:
- Glyceraldehyde-3-phosphate dehydrogenase
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- GAPDH antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php