BICD2 Antibody
Produktgrößen
0.1 mg
£652,00
OAPB00708-0.1MG
Über dieses Produkt
- SKU:
- OAPB00708
- Zusätzliche Namen:
- bA526D8.1;bicaudal D homolog 2;bic-D 2;coiled-coil protein BICD2;cytoskeleton-like bicaudal D protein homolog 2;homolog of Drosophila bicaudal D;protein bicaudal D homolog 2;SMALED2;SMALED2A;SMALED2B.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (By similarity). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex (PubMed:25962623). Contributes to nuclear and centrosomal positioning prior to mitotic entry through regulation of both dynein and kinesin-1. During G2 phase of the cell cycle; associates with RANBP2 at the nuclear pores and recruits dynein and dynactin to the nuclear envelope to ensure proper positioning of the nucleus relative to centrosomes prior to the onset of mitosis (By similarity).
- Gendetails:
- BICD cargo adaptor 2
- Host:
- Rabbit
- Immunogen:
- BICD2 antibody was raised against a 14 amino acid synthetic peptide from near the center of human BICD2. The immunogen is located within amino acids 300 - 350 of BICD2.
- Molekulargewicht:
- Predicted: 94 kDa Observed: 100 kDa
- Proteindetails:
- bicaudal D homolog 2 (Drosophila) [Homo sapiens]|Protein bicaudal D homolog 2
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- BICD2 antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php