DISC1 Antibody
Produktgrößen
0.1 mg
£652,00
OAPB00558-0.1MG
Über dieses Produkt
- SKU:
- OAPB00558
- Zusätzliche Namen:
- C1orf136;disrupted in schizophrenia 1 protein;SCZD9.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus. Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance. Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis; including neuron positioning; dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A. Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development. Plays a role; together with PCNT; in the microtubule network formation.
- Gendetails:
- DISC1 scaffold protein
- Host:
- Rabbit
- Immunogen:
- DISC1 antibody was raised against an 18 amino acid synthetic peptide from near the center of human DISC1. The immunogen is located within amino acids 350 - 400 of DISC1.
- Molekulargewicht:
- Predicted: 72; 92; 94 kDa Observed: 94 kDa
- Proteindetails:
- Disrupted in schizophrenia 1 protein|disrupted in schizophrenia 1 protein isoform L [Homo sapiens]
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- DISC1 antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php