4E-BP1 Antibody
Produktgrößen
0.1 mg
£652,00
OAPB00309-0.1MG
Über dieses Produkt
- SKU:
- OAPB00309
- Zusätzliche Namen:
- 4EBP1;4E-BP1;BP-1;eIF4E-binding protein 1;eukaryotic translation initiation factor 4E-binding protein 1;PHAS-I;phosphorylated heat- and acid-stable protein regulated by insulin 1.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E; leading to repress translation. In contrast; hyperphosphorylated form dissociates from EIF4E; allowing interaction between EIF4G1/EIF4G3 and EIF4E; leading to initiation of translation. Mediates the regulation of protein translation by hormones; growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
- Gendetails:
- eukaryotic translation initiation factor 4E binding protein 1
- Host:
- Rabbit
- Immunogen:
- 4E-BP1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human 4E-BP1. The immunogen is located within the last 50 amino acids of 4E-BP1.
- Proteindetails:
- Eukaryotic translation initiation factor 4E-binding protein 1|eukaryotic translation initiation factor 4E-binding protein 1 [Homo sapiens]
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 4E-BP1 antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php