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Antikörper

CASP1 Antibody

Produktgrößen
0.1 mg
£652,00
OAPB00287-0.1MG
Über dieses Produkt
SKU:
OAPB00287
Zusätzliche Namen:
CASP1 nirs variant 1;caspase 1; apoptosis-related cysteine peptidase;caspase-1;caspase-1 isoform alpha;ICE;IL-1 beta-converting enzyme;IL1BC;IL1B-convertase;interleukin 1; beta; convertase;interleukin 1-B converting enzyme;Interleukin-1 beta convertase;Interleukin-1 beta-converting enzyme;P45.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Konzentration:
1 mg/ml
Weitere Details:
Thiol protease that cleaves IL-1 beta between an Asp and an Ala; releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation; during DNA virus infection but not RNA virus challenge; controls antiviral immunity through the cleavage of CGAS; rendering it inactive (PubMed:28314590).
Gendetails:
caspase 1
Host:
Rabbit
Immunogen:
Caspase-1 antibody was raised against a 15 amino acid synthetic peptide from near the middle of human Caspase-1. The immunogen is located within amino acids 200 - 250 of Caspase-1.
Proteindetails:
Caspase-1|caspase-1 isoform alpha precursor [Homo sapiens]
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Caspase-1 antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody