Bcl-2 Antibody
Produktgrößen
0.1 mg
£652,00
OAPB00242-0.1MG
Über dieses Produkt
- SKU:
- OAPB00242
- Zusätzliche Namen:
- apoptosis regulator Bcl-2;B-cell CLL/lymphoma 2;Bcl-2;PPP1R50;protein phosphatase 1; regulatory subunit 50.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation; hence CASP1 activation and IL1B release (PubMed:17418785).
- Gendetails:
- BCL2 apoptosis regulator
- Host:
- Rabbit
- Immunogen:
- Anti-Bcl-2 antibody (3335) was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Bcl-2. The immunogen is located within the first 50 amino acids of Bcl-2.
- Isotyp:
- IgG
- Molekulargewicht:
- Predicted: 26kD Observed: 26 kD
- Proteindetails:
- Apoptosis regulator Bcl-2|B-cell CLL/lymphoma 2 [Homo sapiens]
- Aufreinigung:
- Ion Exchange
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Bcl-2antibody can be stored at 4C; for three months and -20C stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php