APOBEC3G Antibody
Produktgrößen
0.1 mg
£652,00
OAPB00226-0.1MG
Über dieses Produkt
- SKU:
- OAPB00226
- Zusätzliche Namen:
- A3G;APOBEC-related cytidine deaminase;APOBEC-related protein 9;apolipoprotein B editing enzyme catalytic polypeptide-like 3G;apolipoprotein B mRNA editing enzyme cytidine deaminase;apolipoprotein B mRNA editing enzyme; catalytic polypeptide-like 3G;apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3G;ARCD;ARP9;ARP-9;bK150C2.7;CEM15;CEM-15;deoxycytidine deaminase;dJ494G10.1;DNA dC->dU editing enzyme;DNA dC->dU-editing enzyme APOBEC-3G;MDS019;phorbolin-like protein MDS019.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits potent antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription; it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA; leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome; along with a deamination-independent mechanism that works prior to the proviral integration; together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity also against simian immunodeficiency viruses (SIVs); hepatitis B virus (HBV); equine infectious anemia virus (EIAV); xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV). May inhibit the mobility of LTR and non-LTR retrotransposons.
- Gendetails:
- apolipoprotein B mRNA editing enzyme catalytic subunit 3G
- Host:
- Rabbit
- Immunogen:
- APOBEC3G antibody was raised against a synthetic peptide corresponding to 15 amino acids near the amino-terminus of human APOBEC3G. The immunogen is located within the first 50 amino acids of APOBEC3G.
- Proteindetails:
- DNA dC->dU-editing enzyme APOBEC-3G|DNA dC->dU-editing enzyme APOBEC-3G isoform 1 [Homo sapiens]
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- APOBEC3G antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php