CASP8AP2 Antibody
Produktgrößen
0.1 mg
£652,00
OAPB00106-0.1MG
Über dieses Produkt
- SKU:
- OAPB00106
- Zusätzliche Namen:
- CASP8-associated protein 2;CED-4;FLASH;FLASH homolog RIP25;FLICE associated huge;FLICE-associated huge protein;human FLASH;RIP25.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Participates in TNF-alpha-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level; upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation. Involved in TNF-alpha-induced activation of NF-kappa-B via a TRAF2-dependent pathway. Acts as a downstream mediator for CASP8-induced activation of NF-kappa-B. Required for the activation of CASP8 in FAS-mediated apoptosis. Required for histone gene transcription and progression through S phase.
- Gendetails:
- caspase 8 associated protein 2
- Host:
- Rabbit
- Immunogen:
- FLASH antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human FLASH which differ from those of mouse by one amino acid. The immunogen is located within the last 50 amino acids of FLASH.
- Molekulargewicht:
- 220 kDa
- Proteindetails:
- CASP8-associated protein 2|Homo sapiens FLASH mRNA; partial cds
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- FLASH antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php