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Antikörper

FZD9 Antibody

Produktgrößen
50 µg
£684,00
OALA00933-50UG
Über dieses Produkt
SKU:
OALA00933
Zusätzliche Namen:
FZD9; CD349; Frizzled homolog 9; Fz-9; Frizzled family receptor 9; Frizzled-9; Frizzled 9; Fz9; HFz9; CD349 antigen; Frizzled homolog fzd3; FzE6
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Konzentration:
1 mg/ml
Weitere Details:
Receptor for WNT2 that is coupled to the beta-catenin canonical signaling pathway; which leads to the activation of disheveled proteins; inhibition of GSK-3 kinase; nuclear accumulation of beta-catenin and activation of Wnt target genes. Plays a role in neuromuscular junction (NMJ) assembly by negatively regulating the clustering of acetylcholine receptors (AChR) through the beta-catenin canonical signaling pathway. May play a role in neural progenitor cells (NPCs) viability through the beta-catenin canonical signaling pathway by negatively regulating cell cycle arrest leading to inhibition of neuron apoptotic process. During hippocampal development; regulates neuroblast proliferation and apoptotic cell death. Controls bone formation through non canonical Wnt signaling mediated via ISG15. Positively regulates bone regeneration through non canonical Wnt signaling.
Host:
Rabbit
Immunogen:
Synthetic 17 amino acid peptide from 3rd extracellular domain of human FZD9 / Frizzled 9. Percent identity with other species by BLAST analysis: Human; Gibbon (100%); Mouse; Rat; Dog; Panda (94%); Bat; Bovine; Hamster; Opossum (88%); Rabbit (82%).
Aufreinigung:
Immunoaffinity purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Aliquot and store undiluted at -20C or below for up to 1 year. Can be stored undiluted at 4C for up to 1 month. Avoid freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody