FANCD2 Antibody
Produktgrößen
100ul
£630,00
OAGA08811-100UL
Über dieses Produkt
- SKU:
- OAGA08811
- Zusätzliche Namen:
- FA4; FAD; FACD; FAD2; FA-D2; FANCD
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The Fanconi anemia complementation group (FANC) currently includes FANCA; FANCB; FANCC; FANCD1 (also called BRCA2); FANCD2; FANCE; FANCF; FANCG; FANCI; FANCJ (also called BRIP1); FANCL; FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability; hypersensitivity to DNA crosslinking agents; increased chromosomal breakage; and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage; resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants.
- Gendetails:
- Fanconi anemia complementation group D2
- Host:
- Mouse
- Immunogen:
- Human FANCD2 fusion protein
- Isotyp:
- IgG
- Proteindetails:
- Fanconi anemia group D2 protein
- Aufreinigung:
- Protein G purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php