E2F1 Antibody
Produktgrößen
100ul
£630,00
OAGA08744-100UL
Über dieses Produkt
- SKU:
- OAGA08744
- Zusätzliche Namen:
- RBP3; E2F-1; RBAP1; RBBP3
- translate.label.attr.clone:
- 10D1 2B5
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain; a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP); a transactivation domain enriched in acidic amino acids; and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members; E2F2 and E2F3; have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
- Gendetails:
- E2F transcription factor 1
- Host:
- Mouse
- Immunogen:
- The region encoding the DP-1 binding site (amino acids 223-332) of E2F-1 expressed in E. coli.
- Isotyp:
- IgG2b
- Proteindetails:
- transcription factor E2F1
- Aufreinigung:
- Protein G purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php