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Antikörper

CSE1L Antibody

Produktgrößen
100ul
£630,00
OAGA08483-100UL
Über dieses Produkt
SKU:
OAGA08483
Zusätzliche Namen:
CAS; CSE1; XPO2
translate.label.attr.clone:
GT729
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS; while importin-beta mediates translocation through the nuclear pore complex. After translocation; RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm; leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha; and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition; the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene.
Gendetails:
chromosome segregation 1 like
Host:
Mouse
Immunogen:
Recombinant protein encompassing a sequence within the center region of human CSE1L. The exact sequence is proprietary.
Isotyp:
IgG2a
Proteindetails:
exportin-2
Aufreinigung:
Affinity purified by Protein G.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Monoclonal Antibody